The involvement of HPV in cervical oncogenesis
نویسندگان
چکیده
Results HPV-HR (high-risk) was positive in 377 cases, HPV-LR (low-risk) was positive in 165 cases and in 35 cases no HPV typing was performed. The herpes virus type 2 infection was present in 2 cases. Cytology showed LSIL (low grade squamous intraepithelial lesion) in 329 cases and HSIL (high grade squamous intraepithelial lesion) in 189 cases. Histological examination revealed cervical intraepithelial neoplasia (CIN) I in 69 cases and CIN II, CIN III in 183 cases and carcinoma in situ in 6 cases. HSIL cases all presented infection with HR (16, 18, 31) strains.
منابع مشابه
Distribution of HPV Genotypes and Involvement of Risk Factors in Cervical Lesions and Invasive Cervical Cancer: A Study in an Indian Population
Human papilloma virus (HPV) is considered as the main sexually transmitted etiological agent for the cause and progression of preneoplastic cervical lesions to cervical cancer. This study is discussing the prevalence of HPV and its genotypes in cervical lesions and invasive cervical cancer tissues and their association with various risk factors in women from Varanasi and its adjoining areas in ...
متن کاملPnm-17: Cost Effectiveness of Human Papillomavirus Testing in Cervical Cancer Diagnosis
Background: Epidemiological studies are shown robust association between human papillomavirus (HPV) and cervical cancer. From 1990 HPV was known as a necessary but insufficient cause of cervical invasive cancer. The purpose of this study was to evaluate the cost effectiveness of HPV test in cervical cancer screening. Materials and Methods: This is a systematic review article; the newest scienti...
متن کاملMolecular Identification of Human Papiloma Virus (HPV) in Cervical Neoplasia and the Risk Factors Affecting Cervical Cancer in Isfahan
The rate of cervical cancer in Asians is deferent, based on the risk factors affecting and the rate of papiloma virus infection among females. Cervical cancer is one of the important cancers between Iranian women. In the present study the rate of cervical neoplasia was detected in Isfahan and some risk factors affecting the incidence of cervical cancer was analyzed. The human papiloma virus inf...
متن کاملCorrelation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study
Background: This research was accomplished to evaluate the IHC expression of p16 (ink4a) and CK17 in low grade cervical intraepithelial lesions (LSIL), high grade cervical intraepithelial lesions (HSIL) and invasive cervical carcinomas and to assess their correlation to HPV (16E6+18E6). Methods: The study...
متن کاملCorrelation between histopathological criteria of Human Papilloma Virus infection and the presence of HPV in paraffin-embedded cervical biopsies based on PCR assay
Introduction: This study was carried out to correlate histological findings in cervical lesions to human papilloma virus (HPV), as detected by polymerase chain reaction (PCR). Methods: In this descriptive study, out of 143 cervical biopsies, 50 biopsies, containing sufficient histopathologic criteria, were examined. PCR assay was performed with the primers GP05/06+ and, as control, the beta-glo...
متن کامل